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Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes serious infections in immunocompromised individuals and cystic fibrosis patients. ExoS and ExoT are two homologous bifunctional Type III Secretion System (T3SS) virulence factors that induce apoptosis in target host cells....

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Detalles Bibliográficos
Autores principales:	Kaminski, Amber, Gupta, Kajal H., Goldufsky, Josef W., Lee, Ha Won, Gupta, Vineet, Shafikhani, Sasha H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145893/ https://www.ncbi.nlm.nih.gov/pubmed/30232373 http://dx.doi.org/10.1038/s41598-018-32491-2

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