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Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators
Osteoblasts are responsible for the maintenance of bone homeostasis. Deregulation of their differentiation is etiologically linked to several bone disorders, making this process an important target for therapeutic intervention. Systemic identification of osteoblast regulators has been hampered by th...
Autores principales: | Ahmad, Mubashir, Kroll, Torsten, Jakob, Jeanette, Rauch, Alexander, Ploubidou, Aspasia, Tuckermann, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145911/ https://www.ncbi.nlm.nih.gov/pubmed/30232406 http://dx.doi.org/10.1038/s41598-018-32364-8 |
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