Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments

In human inflammatory sites, PD-1(hi)CXCR5(−)CD4(+) T cells are involved in the formation of ectopic lymphoid-like structures (ELSs) by the secretion of chemokine CXCL13, but how the transcription of CXCL13 is regulated in CD4(+) T cells is still unclear. Here we show that Sox4 is a key transcriptio...

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Detalles Bibliográficos
Autores principales: Yoshitomi, Hiroyuki, Kobayashi, Shio, Miyagawa-Hayashino, Aya, Okahata, Akinori, Doi, Kohei, Nishitani, Kohei, Murata, Koichi, Ito, Hiromu, Tsuruyama, Tatsuaki, Haga, Hironori, Matsuda, Shuichi, Toguchida, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145936/
https://www.ncbi.nlm.nih.gov/pubmed/30232328
http://dx.doi.org/10.1038/s41467-018-06187-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145936/
https://www.ncbi.nlm.nih.gov/pubmed/30232328
http://dx.doi.org/10.1038/s41467-018-06187-0

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