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Inhibition of NKCC1 Modulates Alveolar Fluid Clearance and Inflammation in Ischemia-Reperfusion Lung Injury via TRAF6-Mediated Pathways

Background: The expression of Na-K-2Cl cotransporter 1 (NKCC1) in the alveolar epithelium is responsible for fluid homeostasis in acute lung injury (ALI). Increasing evidence suggests that NKCC1 is associated with inflammation in ALI. We hypothesized that inhibiting NKCC1 would attenuate ALI after i...

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Detalles Bibliográficos
Autores principales:	Shen, Chih-Hao, Lin, Jr-Yu, Chang, Yung-Lung, Wu, Shu-Yu, Peng, Chung-Kan, Wu, Chin-Pyng, Huang, Kun-Lun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146090/ https://www.ncbi.nlm.nih.gov/pubmed/30271405 http://dx.doi.org/10.3389/fimmu.2018.02049

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