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MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources

The ever-increasing metagenomic data necessitate appropriate cataloguing in a way that facilitates the comparison and better contextualization of the underlying investigations. To this extent, information associated with the sequencing data as well as the original sample and the environment where it...

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Autores principales: Marks, Peter C, Bigler, Marc, Alsop, Eric B, Vigneron, Adrien, Lomans, Bart P, De Paula, Renato, Geissler, Brett, Tsesmetzis, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146120/
https://www.ncbi.nlm.nih.gov/pubmed/30212909
http://dx.doi.org/10.1093/database/bay087
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author Marks, Peter C
Bigler, Marc
Alsop, Eric B
Vigneron, Adrien
Lomans, Bart P
De Paula, Renato
Geissler, Brett
Tsesmetzis, Nicolas
author_facet Marks, Peter C
Bigler, Marc
Alsop, Eric B
Vigneron, Adrien
Lomans, Bart P
De Paula, Renato
Geissler, Brett
Tsesmetzis, Nicolas
author_sort Marks, Peter C
collection PubMed
description The ever-increasing metagenomic data necessitate appropriate cataloguing in a way that facilitates the comparison and better contextualization of the underlying investigations. To this extent, information associated with the sequencing data as well as the original sample and the environment where it was obtained from is crucial. To date, there are not any publicly available repositories able to capture environmental metadata pertaining to hydrocarbon-rich environments. As such, contextualization and comparative analysis among sequencing datasets derived from these environments is to a certain degree hindered or cannot be fully evaluated. The metagenomics data management system for hydrocarbon resources (MetaHCRs) enables the capturing of marker gene and whole metagenome sequencing data as well as over 300 contextual attributes associated with samples, organisms, environments and geological properties, among others. Moreover, MetaHCR implements the Minimum Information about any Sequence–hydrocarbon resource specification from the Genomic Standards Consortium; it integrates a user-friendly web interface and relational database model, and it enables the generation of complex custom search. MetaHCR has been tested with 36 publicly available metagenomic studies, and its modular architecture can be easily customized for other types of environmental and metagenomics studies.
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spelling pubmed-61461202018-09-25 MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources Marks, Peter C Bigler, Marc Alsop, Eric B Vigneron, Adrien Lomans, Bart P De Paula, Renato Geissler, Brett Tsesmetzis, Nicolas Database (Oxford) Original Article The ever-increasing metagenomic data necessitate appropriate cataloguing in a way that facilitates the comparison and better contextualization of the underlying investigations. To this extent, information associated with the sequencing data as well as the original sample and the environment where it was obtained from is crucial. To date, there are not any publicly available repositories able to capture environmental metadata pertaining to hydrocarbon-rich environments. As such, contextualization and comparative analysis among sequencing datasets derived from these environments is to a certain degree hindered or cannot be fully evaluated. The metagenomics data management system for hydrocarbon resources (MetaHCRs) enables the capturing of marker gene and whole metagenome sequencing data as well as over 300 contextual attributes associated with samples, organisms, environments and geological properties, among others. Moreover, MetaHCR implements the Minimum Information about any Sequence–hydrocarbon resource specification from the Genomic Standards Consortium; it integrates a user-friendly web interface and relational database model, and it enables the generation of complex custom search. MetaHCR has been tested with 36 publicly available metagenomic studies, and its modular architecture can be easily customized for other types of environmental and metagenomics studies. Oxford University Press 2018-09-13 /pmc/articles/PMC6146120/ /pubmed/30212909 http://dx.doi.org/10.1093/database/bay087 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Marks, Peter C
Bigler, Marc
Alsop, Eric B
Vigneron, Adrien
Lomans, Bart P
De Paula, Renato
Geissler, Brett
Tsesmetzis, Nicolas
MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title_full MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title_fullStr MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title_full_unstemmed MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title_short MetaHCR: a web-enabled metagenome data management system for hydrocarbon resources
title_sort metahcr: a web-enabled metagenome data management system for hydrocarbon resources
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146120/
https://www.ncbi.nlm.nih.gov/pubmed/30212909
http://dx.doi.org/10.1093/database/bay087
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