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Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study
Background: Few studies examined the effects of combined motor and cognitive rehabilitation in patients with multiple sclerosis (MS). The present prospective, multicenter, observational study aimed to determine the efficacy of an integrated cognitive and neuromotor rehabilitation program versus a tr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146227/ https://www.ncbi.nlm.nih.gov/pubmed/30271331 http://dx.doi.org/10.3389/fnbeh.2018.00196 |
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author | Barbarulo, Anna M. Lus, Giacomo Signoriello, Elisabetta Trojano, Luigi Grossi, Dario Esposito, Mariateresa Costabile, Teresa Lanzillo, Roberta Saccà, Francesco Morra, Vincenzo Brescia Conchiglia, Giovannina |
author_facet | Barbarulo, Anna M. Lus, Giacomo Signoriello, Elisabetta Trojano, Luigi Grossi, Dario Esposito, Mariateresa Costabile, Teresa Lanzillo, Roberta Saccà, Francesco Morra, Vincenzo Brescia Conchiglia, Giovannina |
author_sort | Barbarulo, Anna M. |
collection | PubMed |
description | Background: Few studies examined the effects of combined motor and cognitive rehabilitation in patients with multiple sclerosis (MS). The present prospective, multicenter, observational study aimed to determine the efficacy of an integrated cognitive and neuromotor rehabilitation program versus a traditional neuromotor training on walking, balance, cognition and emotional functioning in MS patients. Methods: Sixty three MS patients were selected and assigned either to the Integrated Treatment Group (ITG; n = 32), receiving neuropsychological treatment (performed by ERICA software and paper–pencil tasks) complemented by conventional neuromotor rehabilitation, or to the Motor Treatment Group (n = 31) receiving neuromotor rehabilitation only. The intervention included two 60-min sessions per week for 24 weeks. At baseline and at end of the training all patients underwent a wide-range neuropsychological, psychological/emotional, and motor assessment. Results: At baseline the two groups did not differ for demographic, neuropsychological, psychological/emotional, and motor features significantly. After rehabilitation, only ITG group significantly (p-corrected for False Discovery Rate) improved on test tapping spatial memory, attention and cognitive flexibility, as well as on scales assessing depression and motor performance (balance and gait). A regression analysis showed that neuropsychological and motor improvement was not related to improvements in fatigue and depression. Conclusion: The present study demonstrated positive effects in emotional, motor, and cognitive aspects in MS patients who received an integrated cognitive and neuromotor training. Overall, results are supportive of interventions combining motor and cognitive training for MS. |
format | Online Article Text |
id | pubmed-6146227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-61462272018-09-28 Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study Barbarulo, Anna M. Lus, Giacomo Signoriello, Elisabetta Trojano, Luigi Grossi, Dario Esposito, Mariateresa Costabile, Teresa Lanzillo, Roberta Saccà, Francesco Morra, Vincenzo Brescia Conchiglia, Giovannina Front Behav Neurosci Neuroscience Background: Few studies examined the effects of combined motor and cognitive rehabilitation in patients with multiple sclerosis (MS). The present prospective, multicenter, observational study aimed to determine the efficacy of an integrated cognitive and neuromotor rehabilitation program versus a traditional neuromotor training on walking, balance, cognition and emotional functioning in MS patients. Methods: Sixty three MS patients were selected and assigned either to the Integrated Treatment Group (ITG; n = 32), receiving neuropsychological treatment (performed by ERICA software and paper–pencil tasks) complemented by conventional neuromotor rehabilitation, or to the Motor Treatment Group (n = 31) receiving neuromotor rehabilitation only. The intervention included two 60-min sessions per week for 24 weeks. At baseline and at end of the training all patients underwent a wide-range neuropsychological, psychological/emotional, and motor assessment. Results: At baseline the two groups did not differ for demographic, neuropsychological, psychological/emotional, and motor features significantly. After rehabilitation, only ITG group significantly (p-corrected for False Discovery Rate) improved on test tapping spatial memory, attention and cognitive flexibility, as well as on scales assessing depression and motor performance (balance and gait). A regression analysis showed that neuropsychological and motor improvement was not related to improvements in fatigue and depression. Conclusion: The present study demonstrated positive effects in emotional, motor, and cognitive aspects in MS patients who received an integrated cognitive and neuromotor training. Overall, results are supportive of interventions combining motor and cognitive training for MS. Frontiers Media S.A. 2018-09-05 /pmc/articles/PMC6146227/ /pubmed/30271331 http://dx.doi.org/10.3389/fnbeh.2018.00196 Text en Copyright © 2018 Barbarulo, Lus, Signoriello, Trojano, Grossi, Esposito, Costabile, Lanzillo, Saccà, Brescia Morra and Conchiglia. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Barbarulo, Anna M. Lus, Giacomo Signoriello, Elisabetta Trojano, Luigi Grossi, Dario Esposito, Mariateresa Costabile, Teresa Lanzillo, Roberta Saccà, Francesco Morra, Vincenzo Brescia Conchiglia, Giovannina Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title | Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title_full | Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title_fullStr | Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title_full_unstemmed | Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title_short | Integrated Cognitive and Neuromotor Rehabilitation in Multiple Sclerosis: A Pragmatic Study |
title_sort | integrated cognitive and neuromotor rehabilitation in multiple sclerosis: a pragmatic study |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146227/ https://www.ncbi.nlm.nih.gov/pubmed/30271331 http://dx.doi.org/10.3389/fnbeh.2018.00196 |
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