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GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson’s disease

We aim to investigate the function and mechanism of GanDouLing combinated with Penicillamine on cerebrovascular injury in Wilson’s disease (WD). ELISA was performed to analyze the expression of vascular injury factors. Pathological changes of cerebral vessels were observed by HE stain. Immunohistoch...

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Detalles Bibliográficos
Autores principales: Chen, Yonghua, Zhang, Bo, Cao, Shijian, Huang, Wei, Liu, Ni, Yang, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146297/
https://www.ncbi.nlm.nih.gov/pubmed/30181379
http://dx.doi.org/10.1042/BSR20180800