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Ketamine influences the locus coeruleus norepinephrine network, with a dependency on norepinephrine transporter genotype – a placebo controlled fMRI study

BACKGROUND: Ketamine is receiving increasing attention as a rapid-onset antidepressant in patients suffering from major depressive disorder (MDD) with treatment resistance or severe suicidal ideation. Ketamine modulates several neurotransmitter systems, including norepinephrine via the norepinephrin...

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Detalles Bibliográficos
Autores principales: Liebe, Thomas, Li, Meng, Colic, Lejla, Munk, Matthias H.J., Sweeney-Reed, Catherine M., Woelfer, Marie, Kretzschmar, Moritz A., Steiner, Johann, von Düring, Felicia, Behnisch, Gusalija, Schott, Björn H., Walter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146384/
https://www.ncbi.nlm.nih.gov/pubmed/30238915
http://dx.doi.org/10.1016/j.nicl.2018.09.001