Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series

Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoro-anilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-...

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Autores principales: Pavličić, Davorka, Koružnjak, Jasna Dogan, Banić-Tomišić, Zrinka, Karminski-Zamola, Grace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2002
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146432/
http://dx.doi.org/10.3390/71200871
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author Pavličić, Davorka
Koružnjak, Jasna Dogan
Banić-Tomišić, Zrinka
Karminski-Zamola, Grace
author_facet Pavličić, Davorka
Koružnjak, Jasna Dogan
Banić-Tomišić, Zrinka
Karminski-Zamola, Grace
author_sort Pavličić, Davorka
collection PubMed
description Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoro-anilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b]furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders.
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spelling pubmed-61464322018-11-19 Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series Pavličić, Davorka Koružnjak, Jasna Dogan Banić-Tomišić, Zrinka Karminski-Zamola, Grace Molecules Article Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoro-anilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b]furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders. MDPI 2002-12-31 /pmc/articles/PMC6146432/ http://dx.doi.org/10.3390/71200871 Text en © 2002 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Pavličić, Davorka
Koružnjak, Jasna Dogan
Banić-Tomišić, Zrinka
Karminski-Zamola, Grace
Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title_full Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title_fullStr Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title_full_unstemmed Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title_short Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
title_sort synthesis of some new bis-(p-fluorophenyl)amides of the thieno[3,2-b]thiophene, thieno[3,2-b]furan and 1,2-bis{5-[2-(2-thienyl)ethenyl]2-thienyl}ethene series
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146432/
http://dx.doi.org/10.3390/71200871
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