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A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)- hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging.

The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT(2A) serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a link...

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Detalles Bibliográficos
Autores principales: Tomlinson, Ian D., Grey, Jesse L., Rosenthal, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146450/
http://dx.doi.org/10.3390/71100777
Descripción
Sumario:The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT(2A) serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications  in biological assays and biological imaging.