Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared...

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Detalles Bibliográficos
Autores principales: Fathalla, Walid M., Pazdera, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146461/
http://dx.doi.org/10.3390/70100096
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author Fathalla, Walid M.
Pazdera, Pavel
author_facet Fathalla, Walid M.
Pazdera, Pavel
author_sort Fathalla, Walid M.
collection PubMed
description The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
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spelling pubmed-61464612018-11-19 Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides Fathalla, Walid M. Pazdera, Pavel Molecules Article The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed. MDPI 2002-01-30 /pmc/articles/PMC6146461/ http://dx.doi.org/10.3390/70100096 Text en © 2002 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Fathalla, Walid M.
Pazdera, Pavel
Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_full Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_fullStr Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_full_unstemmed Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_short Synthesis of Heterocyclic Skeletons by the Reaction of N(1)-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_sort synthesis of heterocyclic skeletons by the reaction of n(1)-(2-cyanophenyl)-benzimidoyl chloride with thioamides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146461/
http://dx.doi.org/10.3390/70100096
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