Cargando…

The functional diversity of Aurora kinases: a comprehensive review

Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit distinct cellular and subcellular localization. AurA favors the G2/M transition by promoting centrosome maturation and mit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Willems, Estelle, Dedobbeleer, Matthias, Digregorio, Marina, Lombard, Arnaud, Lumapat, Paul Noel, Rogister, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146527/ https://www.ncbi.nlm.nih.gov/pubmed/30250494 http://dx.doi.org/10.1186/s13008-018-0040-6

Ejemplares similares

Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration
por: Willems, Estelle, et al.
Publicado: (2018)

The expression of B7-H3 isoforms in newly diagnosed glioblastoma and recurrence and their functional role
por: Digregorio, Marina, et al.
Publicado: (2021)

Relevance of Translation Initiation in Diffuse Glioma Biology and its Therapeutic Potential
por: Marina, Digregorio, et al.
Publicado: (2019)

The Subventricular Zone, a Hideout for Adult and Pediatric High-Grade Glioma Stem Cells
por: Lombard, Arnaud, et al.
Publicado: (2021)

Communicating hydrocephalus associated to ventral leptomeningeal invasion leads to precocious death in a glioblastoma orthotopic xenograft model
por: Lombard, Arnaud, et al.
Publicado: (2020)

The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation
por: D’Arrigo, Paolo, et al.
Publicado: (2019)

Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone
por: Da-Veiga, Marc-Antoine, et al.
Publicado: (2023)

Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review
por: Gavriilidis, Paschalis, et al.
Publicado: (2015)

Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
por: Hochegger, Helfrid, et al.
Publicado: (2013)

Pharmacophore Synergism in Diverse Scaffold Clinches in Aurora Kinase B
por: Masand, Vijay H., et al.
Publicado: (2022)

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins
por: Carmena, Mar, et al.
Publicado: (2009)

Functions of Aurora kinase C in meiosis and cancer
por: Quartuccio, Suzanne M., et al.
Publicado: (2015)

Diverse Functionalization of Aurora-A Kinase at Specified Surface and Buried Sites by Native Chemical Modification
por: Rowan, Fiona, et al.
Publicado: (2014)

Aurora kinases in ovarian cancer
por: Pérez-Fidalgo, J Alejandro, et al.
Publicado: (2020)

Selective Disruption of Aurora C Kinase Reveals Distinct Functions from Aurora B Kinase during Meiosis in Mouse Oocytes
por: Balboula, Ahmed Z., et al.
Publicado: (2014)

Patient-Oriented Perspective on Chemokine Receptor Expression and Function in Glioma
por: Isci, Damla, et al.
Publicado: (2021)

Glioma Stem Cells in Pediatric High-Grade Gliomas: From Current Knowledge to Future Perspectives
por: Da-Veiga, Marc-Antoine, et al.
Publicado: (2022)

Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target
por: Hartsink-Segers, S A, et al.
Publicado: (2013)

The Aurora Kinases in Cell Cycle and Leukemia
por: Goldenson, Benjamin, et al.
Publicado: (2014)

Ubiquitin-Mediated Degradation of Aurora Kinases
por: Lindon, Catherine, et al.
Publicado: (2016)

Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex
por: Altiner, Pinar, et al.
Publicado: (2023)

Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
por: Lim, Yoon, et al.
Publicado: (2020)

Aurora kinase inhibitors: Progress towards the clinic
por: Kollareddy, Madhu, et al.
Publicado: (2012)

Aurora Kinase Inhibitors: Current Status and Outlook
por: Bavetsias, Vassilios, et al.
Publicado: (2015)

The multifaceted allosteric regulation of Aurora kinase A
por: Levinson, Nicholas Mark
Publicado: (2018)

Aurora kinases: novel therapy targets in cancers
por: Tang, Anqun, et al.
Publicado: (2017)

Aurora A Protein Kinase: To the Centrosome and Beyond
por: Magnaghi-Jaulin, Laura, et al.
Publicado: (2019)

Cdc7 kinase stimulates Aurora B kinase in M-phase
por: Ito, Sayuri, et al.
Publicado: (2019)

Functional Significance of Aurora Kinases–p53 Protein Family Interactions in Cancer
por: Sasai, Kaori, et al.
Publicado: (2016)

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability
por: Williams, Monique M., et al.
Publicado: (2019)

Medication-Related Osteonecrosis of the Jaw: New Insights into Molecular Mechanisms and Cellular Therapeutic Approaches
por: Lombard, Thomas, et al.
Publicado: (2016)

Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib
por: Steeghs, Neeltje, et al.
Publicado: (2010)

Rapid calcium-dependent activation of Aurora-A kinase
por: Plotnikova, Olga V., et al.
Publicado: (2010)

Aurora B: Hooking up with cyclin-dependent kinases
por: Poon, Randy Y.C.
Publicado: (2013)

Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma
por: Tavanti, E, et al.
Publicado: (2013)

Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells
por: Michaelis, Martin, et al.
Publicado: (2014)

Evolutionary Reconstruction and Population Genetics Analysis of Aurora Kinases
por: Kamaraj, Balu, et al.
Publicado: (2013)

Aurora kinase A in gastrointestinal cancers: time to target
por: Katsha, Ahmed, et al.
Publicado: (2015)

Promising Therapy in Lung Cancer: Spotlight on Aurora Kinases
por: Galetta, Domenico, et al.
Publicado: (2020)

Aurora kinase A is essential for meiosis in mouse oocytes
por: Blengini, Cecilia S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9e58fpuvtfrgvlg6jmidh33drq