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Lithium Perchlorate Mediated Three-Component Preparation of Primary Aminoesters

A three-component reaction between an aldehyde, metallated hexamethyldisilazane and a functionalized organozinc compound proceeded smoothly in the presence of LiClO(4) in diethyl ether to afford primary amino esters in good yields.

Detalles Bibliográficos
Autores principales: Saidi, Mohammad R., Azizi, Najmoddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146534/
http://dx.doi.org/10.3390/70100072
Descripción
Sumario:A three-component reaction between an aldehyde, metallated hexamethyldisilazane and a functionalized organozinc compound proceeded smoothly in the presence of LiClO(4) in diethyl ether to afford primary amino esters in good yields.