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Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide
In this data article, HPLC analyses were applied to investigate the hydrolytic and thermal stability of domiphen bromide a FDA approved OTC ingredients endowed with antimicrobial activity. The data obtained by stressing domiphen bromide in acid, base and thermal conditions enlarge the research artic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146566/ https://www.ncbi.nlm.nih.gov/pubmed/30246118 http://dx.doi.org/10.1016/j.dib.2018.08.152 |
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author | Fumagalli, Laura Moretto, Alessandra Gilardoni, Ettore Picozzi, Claudia Vistoli, Giulio Carini, Marina |
author_facet | Fumagalli, Laura Moretto, Alessandra Gilardoni, Ettore Picozzi, Claudia Vistoli, Giulio Carini, Marina |
author_sort | Fumagalli, Laura |
collection | PubMed |
description | In this data article, HPLC analyses were applied to investigate the hydrolytic and thermal stability of domiphen bromide a FDA approved OTC ingredients endowed with antimicrobial activity. The data obtained by stressing domiphen bromide in acid, base and thermal conditions enlarge the research article published by Fumagalli et al. [2]. The chromatograms herein presented reveal that domiphen bromide is stable under acidic and thermal stress while the treatment with base yield to a by-product. The para-bromo derivative, p-bromodomiphen bromide shows the same behavior under the up mentioned stressed conditions. |
format | Online Article Text |
id | pubmed-6146566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-61465662018-09-21 Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide Fumagalli, Laura Moretto, Alessandra Gilardoni, Ettore Picozzi, Claudia Vistoli, Giulio Carini, Marina Data Brief Chemistry In this data article, HPLC analyses were applied to investigate the hydrolytic and thermal stability of domiphen bromide a FDA approved OTC ingredients endowed with antimicrobial activity. The data obtained by stressing domiphen bromide in acid, base and thermal conditions enlarge the research article published by Fumagalli et al. [2]. The chromatograms herein presented reveal that domiphen bromide is stable under acidic and thermal stress while the treatment with base yield to a by-product. The para-bromo derivative, p-bromodomiphen bromide shows the same behavior under the up mentioned stressed conditions. Elsevier 2018-08-31 /pmc/articles/PMC6146566/ /pubmed/30246118 http://dx.doi.org/10.1016/j.dib.2018.08.152 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Chemistry Fumagalli, Laura Moretto, Alessandra Gilardoni, Ettore Picozzi, Claudia Vistoli, Giulio Carini, Marina Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title | Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title_full | Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title_fullStr | Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title_full_unstemmed | Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title_short | Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
title_sort | data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146566/ https://www.ncbi.nlm.nih.gov/pubmed/30246118 http://dx.doi.org/10.1016/j.dib.2018.08.152 |
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