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Aberrant expression of Twist1 in diseased articular cartilage and a potential role in the modulation of osteoarthritis severity
The bHLH transcription factor Twist1 has emerged as a negative regulator of chondrogenesis in skeletal progenitor cells and as an inhibitor of maturation in growth plate chondrocytes. However, its role in articular cartilage remains obscure. Here we examine Twist1 expression during re-differentiatio...
Autores principales: | Guzzo, Rosa M., Alaee, Farhang, Paglia, David, Gibson, Jason D., Spicer, Douglas, Drissi, Hicham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146614/ https://www.ncbi.nlm.nih.gov/pubmed/30258877 http://dx.doi.org/10.1016/j.gendis.2015.12.005 |
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