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Aberrant expression of Twist1 in diseased articular cartilage and a potential role in the modulation of osteoarthritis severity

The bHLH transcription factor Twist1 has emerged as a negative regulator of chondrogenesis in skeletal progenitor cells and as an inhibitor of maturation in growth plate chondrocytes. However, its role in articular cartilage remains obscure. Here we examine Twist1 expression during re-differentiatio...

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Detalles Bibliográficos
Autores principales: Guzzo, Rosa M., Alaee, Farhang, Paglia, David, Gibson, Jason D., Spicer, Douglas, Drissi, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146614/
https://www.ncbi.nlm.nih.gov/pubmed/30258877
http://dx.doi.org/10.1016/j.gendis.2015.12.005

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