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Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets

BACKGROUND: Prostaglandins are products of the cyclooxygenase pathway, which is implicated in Parkinson’s disease (PD). Limited knowledge is available on mechanisms by which prostaglandins contribute to PD neurodegeneration. To address this gap, we focused on the prostaglandin PGD2/J2 signaling path...

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Detalles Bibliográficos
Autores principales:	Corwin, Chuhyon, Nikolopoulou, Anastasia, Pan, Allen L., Nunez-Santos, Mariela, Vallabhajosula, Shankar, Serrano, Peter, Babich, John, Figueiredo-Pereira, Maria E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146649/ https://www.ncbi.nlm.nih.gov/pubmed/30236122 http://dx.doi.org/10.1186/s12974-018-1305-3

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