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Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone

BACKGROUND: Denosumab has been shown to reduce tumor size and progression, reform mineralized bone, and increase intralesional bone density in patients with giant cell tumor of bone (GCTB); however, radiologic assessment of tumors in bone is challenging. The study objective was to assess tumor respo...

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Detalles Bibliográficos
Autores principales: Engellau, Jacob, Seeger, Leanne, Grimer, Robert, Henshaw, Robert, Gelderblom, Hans, Choy, Edwin, Chawla, Sant, Reichardt, Peter, O’Neal, Michael, Feng, Amy, Jacobs, Ira, Roberts, Zachary J., Braun, Ada, Bach, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146657/
https://www.ncbi.nlm.nih.gov/pubmed/30231890
http://dx.doi.org/10.1186/s12957-018-1478-3