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Absorption Characteristics of Combination Medication of Realgar and Indigo Naturalis: In Vitro Transport across MDCK-MDR1 Cells and In Vivo Pharmacokinetics in Mice after Oral Administration

Realgar and indigo naturalis are clinically combined to treat varieties of leukemia. Exploring the drug-drug interactions might be beneficial to find active substances and develop new targeted drugs. This study aimed at exploring the change of arsenic concentration in mice and across MDCK-MDR1 cells...

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Detalles Bibliográficos
Autores principales:	Zhang, Miao, Guo, Lin, Lin, Long-Fei, Qu, Chang-Hai, Yin, Xing-Bin, Luo, Shi-Lin, Zhang, Xin, Zhang, Hai-Ying, Liang, Xiao, Guan, Jun, Ni, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146668/ https://www.ncbi.nlm.nih.gov/pubmed/30258467 http://dx.doi.org/10.1155/2018/6493630

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