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PARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type
Epstein Barr virus (EBV) is a potentially oncogenic gammaherpesvirus that establishes a chronic, latent infection in memory B cells. The EBV genome persists in infected host cells as a chromatinized episome and is subject to chromatin-mediated regulation. Binding of the host insulator protein CTCF t...
Autores principales: | Lupey-Green, Lena N., Caruso, Lisa B., Madzo, Jozef, Martin, Kayla A., Tan, Yinfei, Hulse, Michael, Tempera, Italo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146685/ https://www.ncbi.nlm.nih.gov/pubmed/29976663 http://dx.doi.org/10.1128/JVI.00755-18 |
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