The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema

Breakdown of the blood–brain barrier (BBB) or inner blood–retinal barrier (BRB), induced by pathologically elevated levels of vascular endothelial growth factor (VEGF) or other mediators, can lead to vasogenic edema and significant clinical problems such as neuronal morbidity and mortality, or visio...

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Detalles Bibliográficos
Autores principales: Bosma, Esmeralda K., van Noorden, Cornelis J. F., Schlingemann, Reinier O., Klaassen, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146740/
https://www.ncbi.nlm.nih.gov/pubmed/30231925
http://dx.doi.org/10.1186/s12987-018-0109-2

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