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Activation of RAAS in a rat model of liver cirrhosis: no effect of losartan on renal sodium excretion

BACKGROUND: Liver cirrhosis is characterized by avid sodium retention where the activation of the renin angiotensin aldosterone system (RAAS) is considered to be the hallmark of the sodium retaining mechanisms. The direct effect of angiotensin II (ANGII) on the AT-1 receptor in the proximal tubules...

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Detalles Bibliográficos
Autores principales:	Fialla, A. D., Schaffalitzky de Muckadell, O. B., Bie, P., Thiesson, H. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146747/ https://www.ncbi.nlm.nih.gov/pubmed/30231858 http://dx.doi.org/10.1186/s12882-018-1039-6

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