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Activation of RAAS in a rat model of liver cirrhosis: no effect of losartan on renal sodium excretion
BACKGROUND: Liver cirrhosis is characterized by avid sodium retention where the activation of the renin angiotensin aldosterone system (RAAS) is considered to be the hallmark of the sodium retaining mechanisms. The direct effect of angiotensin II (ANGII) on the AT-1 receptor in the proximal tubules...
Autores principales: | Fialla, A. D., Schaffalitzky de Muckadell, O. B., Bie, P., Thiesson, H. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146747/ https://www.ncbi.nlm.nih.gov/pubmed/30231858 http://dx.doi.org/10.1186/s12882-018-1039-6 |
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