Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate

3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arene-diazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d). Thiosemicarbazides 2a–d in the presence of bases selectively transform...

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Autores principales: Karpyak, Volodymyr V., Obushak, Mykola D., Ganushchak, Mykola I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146828/
http://dx.doi.org/10.3390/80200263
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author Karpyak, Volodymyr V.
Obushak, Mykola D.
Ganushchak, Mykola I.
author_facet Karpyak, Volodymyr V.
Obushak, Mykola D.
Ganushchak, Mykola I.
author_sort Karpyak, Volodymyr V.
collection PubMed
description 3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arene-diazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d). Thiosemicarbazides 2a–d in the presence of bases selectively transform into 2-(2-R(1)-hydrazino)-5-(R(2)-benzyl)-2-thiazolines (3a–d).
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spelling pubmed-61468282018-11-19 Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate Karpyak, Volodymyr V. Obushak, Mykola D. Ganushchak, Mykola I. Molecules Article 3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arene-diazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d). Thiosemicarbazides 2a–d in the presence of bases selectively transform into 2-(2-R(1)-hydrazino)-5-(R(2)-benzyl)-2-thiazolines (3a–d). MDPI 2003-02-28 /pmc/articles/PMC6146828/ http://dx.doi.org/10.3390/80200263 Text en © 2003 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Karpyak, Volodymyr V.
Obushak, Mykola D.
Ganushchak, Mykola I.
Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title_full Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title_fullStr Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title_full_unstemmed Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title_short Synthesis of 2-(2-R(1)-Hydrazino)-5-(R(2)-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate
title_sort synthesis of 2-(2-r(1)-hydrazino)-5-(r(2)-benzyl)-2-thiazolines on the basis of meerweins arylation products of allyl isothiocyanate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146828/
http://dx.doi.org/10.3390/80200263
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AT ganushchakmykolai synthesisof22r1hydrazino5r2benzyl2thiazolinesonthebasisofmeerweinsarylationproductsofallylisothiocyanate

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