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Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery

BACKGROUND: Native aortic coarctation in young infants can be treated surgically or with balloon angioplasty, although the latter approach remains controversial. We sought to compare midterm outcomes of balloon and surgical coarctoplasty at our center and to review the current practices in literatur...

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Autores principales: Sen, Supratim, Garg, Sandeep, Rao, Suresh G, Kulkarni, Snehal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146845/
https://www.ncbi.nlm.nih.gov/pubmed/30271015
http://dx.doi.org/10.4103/apc.APC_165_17
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author Sen, Supratim
Garg, Sandeep
Rao, Suresh G
Kulkarni, Snehal
author_facet Sen, Supratim
Garg, Sandeep
Rao, Suresh G
Kulkarni, Snehal
author_sort Sen, Supratim
collection PubMed
description BACKGROUND: Native aortic coarctation in young infants can be treated surgically or with balloon angioplasty, although the latter approach remains controversial. We sought to compare midterm outcomes of balloon and surgical coarctoplasty at our center and to review the current practices in literature. METHODS: The study design was a retrospective record review. Patients with coarctation aged <1 year who underwent balloon or surgical coarctoplasty at our center (January 2010–January 2016) with >6-month post-procedure follow-up were studied. Patients with significant arch hypoplasia or interruption, long-segment coarctation, and associated intracardiac lesions were excluded from the study. Clinical, echocardiographic, and procedural details were recorded at initial presentation and follow-up. Need for reintervention was noted. RESULTS: Out of a total of 75 patients, 28 underwent balloon (Group A) and 47 underwent surgical coarctoplasty (Group B). There were two deaths in Group B (mortality 4.2%) and none in Group A. In neonates, 63.6% of Group A and 17.4% of Group B patients required reintervention (P = 0.007). Beyond the neonatal age, 29.4% of Group A and 41.6% of Group B patients required reintervention (not statistically significant). On univariate analysis, residual coarctation on predischarge echocardiogram was the only significant predictor of reintervention (P = 0.04). On Kaplan–Meier analysis, with neonatal presentation, freedom from reintervention in Group B was significantly higher than Group A (P = 0.028). CONCLUSION: In neonates with native aortic coarctation, surgery unequivocally yields better immediate and midterm results and is the preferred treatment modality. In older infants, balloon coarctoplasty has good early and midterm outcomes with acceptable reintervention rates and should be considered a viable alternative to surgery, especially in critical patients with high surgical risk.
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spelling pubmed-61468452018-09-28 Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery Sen, Supratim Garg, Sandeep Rao, Suresh G Kulkarni, Snehal Ann Pediatr Cardiol Original Article BACKGROUND: Native aortic coarctation in young infants can be treated surgically or with balloon angioplasty, although the latter approach remains controversial. We sought to compare midterm outcomes of balloon and surgical coarctoplasty at our center and to review the current practices in literature. METHODS: The study design was a retrospective record review. Patients with coarctation aged <1 year who underwent balloon or surgical coarctoplasty at our center (January 2010–January 2016) with >6-month post-procedure follow-up were studied. Patients with significant arch hypoplasia or interruption, long-segment coarctation, and associated intracardiac lesions were excluded from the study. Clinical, echocardiographic, and procedural details were recorded at initial presentation and follow-up. Need for reintervention was noted. RESULTS: Out of a total of 75 patients, 28 underwent balloon (Group A) and 47 underwent surgical coarctoplasty (Group B). There were two deaths in Group B (mortality 4.2%) and none in Group A. In neonates, 63.6% of Group A and 17.4% of Group B patients required reintervention (P = 0.007). Beyond the neonatal age, 29.4% of Group A and 41.6% of Group B patients required reintervention (not statistically significant). On univariate analysis, residual coarctation on predischarge echocardiogram was the only significant predictor of reintervention (P = 0.04). On Kaplan–Meier analysis, with neonatal presentation, freedom from reintervention in Group B was significantly higher than Group A (P = 0.028). CONCLUSION: In neonates with native aortic coarctation, surgery unequivocally yields better immediate and midterm results and is the preferred treatment modality. In older infants, balloon coarctoplasty has good early and midterm outcomes with acceptable reintervention rates and should be considered a viable alternative to surgery, especially in critical patients with high surgical risk. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6146845/ /pubmed/30271015 http://dx.doi.org/10.4103/apc.APC_165_17 Text en Copyright: © 2018 Annals of Pediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sen, Supratim
Garg, Sandeep
Rao, Suresh G
Kulkarni, Snehal
Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title_full Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title_fullStr Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title_full_unstemmed Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title_short Native aortic coarctation in neonates and infants: Immediate and midterm outcomes with balloon angioplasty and surgery
title_sort native aortic coarctation in neonates and infants: immediate and midterm outcomes with balloon angioplasty and surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146845/
https://www.ncbi.nlm.nih.gov/pubmed/30271015
http://dx.doi.org/10.4103/apc.APC_165_17
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