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Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants

BACKGROUND: In coarctation of aorta associated with proximal arch hypoplasia, extended end-to-end anastomosis through a thoracotomy would result in a residual gradient between the origins of the innominate and the left common carotid arteries. To eliminate this, we modified the surgical technique. P...

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Autores principales: Dharmapuram, Anil Kumar, Ramadoss, Nagarajan, Verma, Sudeep, Vejendla, Goutami, Ivatury, Rao Mrutyunjaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146848/
https://www.ncbi.nlm.nih.gov/pubmed/30271016
http://dx.doi.org/10.4103/apc.APC_5_18
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author Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Verma, Sudeep
Vejendla, Goutami
Ivatury, Rao Mrutyunjaya
author_facet Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Verma, Sudeep
Vejendla, Goutami
Ivatury, Rao Mrutyunjaya
author_sort Dharmapuram, Anil Kumar
collection PubMed
description BACKGROUND: In coarctation of aorta associated with proximal arch hypoplasia, extended end-to-end anastomosis through a thoracotomy would result in a residual gradient between the origins of the innominate and the left common carotid arteries. To eliminate this, we modified the surgical technique. PATIENTS AND METHODS: Between March 2012 and May 2017, 50 patients (14 neonates) underwent repair of coarctation of aorta through a thoracotomy. The age ranged from 6 days to 2 years (median 2 months) and the weight from 1.8 to 8.0 kg (median 4.3 kg). A total of 15 patients (Group A) underwent repair by the extended end-to-end anastomosis. Among them, two patients developed early restenosis at the proximal arch requiring surgical reintervention. Hence, in the second half of the study, 35 patients (Group B) who were identified to have significant hypoplasia of the proximal arch underwent a modified end-to-side anastomosis of the descending aorta to the proximal arch incorporating the distal ascending aorta in the anastomosis and leaving the left subclavian artery end of the isthmus as an end-on vessel. RESULTS: One neonate in Group B died due to a cause not related to the repair. All the other patients in Group B are doing well without a residual gradient during a median follow-up of 23 months. There were no airway issues related to extensive mobilization of the aorta. CONCLUSION: End-to-side anastomosis of the descending aorta to the proximal arch and side of the ascending aorta is possible through a thoracotomy and can be achieved with good outcome in neonates and infants.
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spelling pubmed-61468482018-09-28 Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants Dharmapuram, Anil Kumar Ramadoss, Nagarajan Verma, Sudeep Vejendla, Goutami Ivatury, Rao Mrutyunjaya Ann Pediatr Cardiol Original Article BACKGROUND: In coarctation of aorta associated with proximal arch hypoplasia, extended end-to-end anastomosis through a thoracotomy would result in a residual gradient between the origins of the innominate and the left common carotid arteries. To eliminate this, we modified the surgical technique. PATIENTS AND METHODS: Between March 2012 and May 2017, 50 patients (14 neonates) underwent repair of coarctation of aorta through a thoracotomy. The age ranged from 6 days to 2 years (median 2 months) and the weight from 1.8 to 8.0 kg (median 4.3 kg). A total of 15 patients (Group A) underwent repair by the extended end-to-end anastomosis. Among them, two patients developed early restenosis at the proximal arch requiring surgical reintervention. Hence, in the second half of the study, 35 patients (Group B) who were identified to have significant hypoplasia of the proximal arch underwent a modified end-to-side anastomosis of the descending aorta to the proximal arch incorporating the distal ascending aorta in the anastomosis and leaving the left subclavian artery end of the isthmus as an end-on vessel. RESULTS: One neonate in Group B died due to a cause not related to the repair. All the other patients in Group B are doing well without a residual gradient during a median follow-up of 23 months. There were no airway issues related to extensive mobilization of the aorta. CONCLUSION: End-to-side anastomosis of the descending aorta to the proximal arch and side of the ascending aorta is possible through a thoracotomy and can be achieved with good outcome in neonates and infants. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6146848/ /pubmed/30271016 http://dx.doi.org/10.4103/apc.APC_5_18 Text en Copyright: © 2018 Annals of Pediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Verma, Sudeep
Vejendla, Goutami
Ivatury, Rao Mrutyunjaya
Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title_full Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title_fullStr Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title_full_unstemmed Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title_short Early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
title_sort early outcomes of modification of end to side repair of coarctation of aorta with arch hypoplasia in neonates and infants
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146848/
https://www.ncbi.nlm.nih.gov/pubmed/30271016
http://dx.doi.org/10.4103/apc.APC_5_18
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