Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine

Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, (1)H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecu...

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Autores principales: Song, Bao-An, Wu, Yang-Lan, Yang, Song, Hu, De-Yu, He, Xiang-Qiong, Jin, Lin-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146888/
http://dx.doi.org/10.3390/80100186
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author Song, Bao-An
Wu, Yang-Lan
Yang, Song
Hu, De-Yu
He, Xiang-Qiong
Jin, Lin-Hong
author_facet Song, Bao-An
Wu, Yang-Lan
Yang, Song
Hu, De-Yu
He, Xiang-Qiong
Jin, Lin-Hong
author_sort Song, Bao-An
collection PubMed
description Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, (1)H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray diffraction structure analysis.
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spelling pubmed-61468882018-11-19 Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine Song, Bao-An Wu, Yang-Lan Yang, Song Hu, De-Yu He, Xiang-Qiong Jin, Lin-Hong Molecules Article Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, (1)H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray diffraction structure analysis. MDPI 2003-01-31 /pmc/articles/PMC6146888/ http://dx.doi.org/10.3390/80100186 Text en © 2003 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Song, Bao-An
Wu, Yang-Lan
Yang, Song
Hu, De-Yu
He, Xiang-Qiong
Jin, Lin-Hong
Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title_full Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title_fullStr Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title_full_unstemmed Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title_short Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
title_sort synthesis and bioactivity of a-aminophosphonates containing fluorine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146888/
http://dx.doi.org/10.3390/80100186
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