Structural Determinants of the Stability of Enzyme‐Responsive Polyion Complex Nanoparticles Targeting Pseudomonas aeruginosa’s Elastase

Here, we report how the stability of polyion complex (PIC) particles containing Pseudomonas aeruginosa’s elastase (LasB) degradable peptides and antimicrobial poly(ethylene imine) is significantly improved by careful design of the peptide component. Three LasB‐degradable peptides are reported herein...

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Detalles Bibliográficos
Autores principales: Insua, Ignacio, Petit, Marion, Blackman, Lewis D., Keogh, Robert, Pitto‐Barry, Anaïs, O'Reilly, Rachel K., Peacock, Anna F. A., Krachler, Anne Marie, Fernandez‐Trillo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146907/
https://www.ncbi.nlm.nih.gov/pubmed/30263883
http://dx.doi.org/10.1002/cnma.201800054

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