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Synthesis of Plasmepsin II Inhibitors – Potential Antimalarial Agents

A new series of plasmepsin II (PM II) inhibitors has been prepared based on 4-aminopiperidine-tert-butyl-carbamate (1). These compounds might be useful as antimalarial drugs acting via a new mechanism, and therefore be less susceptible to parasite resistance now often observed with current antimalar...

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Detalles Bibliográficos
Autores principales:	Mueller, Reto, Huerzeler, Marianne, Boss, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146960/ http://dx.doi.org/10.3390/80700556

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