Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/β-Catenin Signaling

Aryl hydrocarbon receptor (AhR) deficiency alters tissue homeostasis. However, how AhR regulates organ maturation and differentiation remains mostly unknown. Liver differentiation entails a polyploidization process fundamental for cell growth, metabolism, and stress responses. Here, we report that A...

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Detalles Bibliográficos
Autores principales: Moreno-Marín, Nuria, Merino, Jaime M., Alvarez-Barrientos, Alberto, Patel, Daxeshkumar P., Takahashi, Shogo, González-Sancho, José M., Gandolfo, Pablo, Rios, Rosa M., Muñoz, Alberto, Gonzalez, Frank J., Fernández-Salguero, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147018/
https://www.ncbi.nlm.nih.gov/pubmed/30240752
http://dx.doi.org/10.1016/j.isci.2018.05.006

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