Biomechanical Control of Lysosomal Secretion Via the VAMP7 Hub: A Tug-of-War between VARP and LRRK1

The rigidity of the cell environment can vary tremendously between tissues and in pathological conditions. How this property may affect intracellular membrane dynamics is still largely unknown. Here, using atomic force microscopy, we show that cells deficient in the secretory lysosome v-SNARE VAMP7...

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Detalles Bibliográficos
Autores principales: Wang, Guan, Nola, Sébastien, Bovio, Simone, Bun, Philippe, Coppey-Moisan, Maïté, Lafont, Frank, Galli, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147023/
https://www.ncbi.nlm.nih.gov/pubmed/30240735
http://dx.doi.org/10.1016/j.isci.2018.05.016

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