The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma

CDV3 is correlated with tumorigenesis and may affect some biological process in cancer. In this study, we explore the role of CDV3 in HCC. According to the TCGA data base, CDV3 is over-expressed in HCC tissues. Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients. In...

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Autores principales: Xiao, Heng, Zhou, Baoyong, Jiang, Ning, Cai, Yunshi, Liu, Xiongwei, Shi, Zhengrong, Li, Ming, Du, Chengyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147043/
https://www.ncbi.nlm.nih.gov/pubmed/30258946
http://dx.doi.org/10.1016/j.gendis.2018.01.003
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author Xiao, Heng
Zhou, Baoyong
Jiang, Ning
Cai, Yunshi
Liu, Xiongwei
Shi, Zhengrong
Li, Ming
Du, Chengyou
author_facet Xiao, Heng
Zhou, Baoyong
Jiang, Ning
Cai, Yunshi
Liu, Xiongwei
Shi, Zhengrong
Li, Ming
Du, Chengyou
author_sort Xiao, Heng
collection PubMed
description CDV3 is correlated with tumorigenesis and may affect some biological process in cancer. In this study, we explore the role of CDV3 in HCC. According to the TCGA data base, CDV3 is over-expressed in HCC tissues. Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients. In HCC samples from our hospital, CDV3 is also enriched in cancer tissues and CDV3 expression associated with HCC pathological T stage. What is more, higher CDV3 expression could forecast poor survival rate in HCC patients. In conclusion, CDV3 is a biomarker of HCC and could be a potential therapeutic target.
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spelling pubmed-61470432018-09-26 The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma Xiao, Heng Zhou, Baoyong Jiang, Ning Cai, Yunshi Liu, Xiongwei Shi, Zhengrong Li, Ming Du, Chengyou Genes Dis Article CDV3 is correlated with tumorigenesis and may affect some biological process in cancer. In this study, we explore the role of CDV3 in HCC. According to the TCGA data base, CDV3 is over-expressed in HCC tissues. Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients. In HCC samples from our hospital, CDV3 is also enriched in cancer tissues and CDV3 expression associated with HCC pathological T stage. What is more, higher CDV3 expression could forecast poor survival rate in HCC patients. In conclusion, CDV3 is a biomarker of HCC and could be a potential therapeutic target. Chongqing Medical University 2018-01-31 /pmc/articles/PMC6147043/ /pubmed/30258946 http://dx.doi.org/10.1016/j.gendis.2018.01.003 Text en © 2018 Chongqing Medical University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Xiao, Heng
Zhou, Baoyong
Jiang, Ning
Cai, Yunshi
Liu, Xiongwei
Shi, Zhengrong
Li, Ming
Du, Chengyou
The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title_full The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title_fullStr The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title_full_unstemmed The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title_short The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
title_sort potential value of cdv3 in the prognosis evaluation in hepatocellular carcinoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147043/
https://www.ncbi.nlm.nih.gov/pubmed/30258946
http://dx.doi.org/10.1016/j.gendis.2018.01.003
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