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Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion

Epithelial-to-mesenchymal transition (EMT) is integral to cancer progression, with considerable evidence that EMT has multiple intermediary stages. Understanding the mechanisms of this stepwise activation is of great interest. We recreated a genetically defined model in which primary cells were immo...

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Detalles Bibliográficos
Autores principales: Bisogno, Laura S., Friedersdorf, Matthew B., Keene, Jack D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147080/
https://www.ncbi.nlm.nih.gov/pubmed/30240757
http://dx.doi.org/10.1016/j.isci.2018.05.011