Cargando…

Signal Transduction: An Exciting Field of Investigation for Small Molecule Drug Discovery

Detalles Bibliográficos
Autor principal:	Halazy, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2003
Materias:	Invited Lecture
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147137/ http://dx.doi.org/10.3390/80400349

Ejemplares similares

Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease
por: Cechetto, Jonathan, et al.
Publicado: (2011)

Purinergic signalling: from discovery to current developments
por: Burnstock, Geoffrey
Publicado: (2014)

A genomic approach to biomarker discovery in human autoimmune diseases
por: Pascual, V
Publicado: (2010)

Triple-color single-molecule imaging for analysis of the role of receptor oligomers in signal transduction
por: Yoshimura, Hideaki
Publicado: (2022)

HLA guided epitope discovery in Type 1 diabetes to generate novel therapeutics
por: Peakman, M
Publicado: (2010)

Immunosurveillance by gamma delta T cells - lessons from the cancer field
por: Hayday, A C, et al.
Publicado: (2010)

Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development
por: Murad, Ferid
Publicado: (2012)

Recognition of Children’s Learning in Educational Research, Policy and Practice: Herbison Invited Lecture, NZARE Annual Conference 2022
por: O’Neill, John
Publicado: (2023)

Bone morphogenetic protein receptor signal transduction in human disease
por: Gomez‐Puerto, Maria Catalina, et al.
Publicado: (2018)

Mechanisms of signal transduction by ethylene: overlapping and non-overlapping signalling roles in a receptor family
por: Shakeel, Samina N., et al.
Publicado: (2013)

The roles of intraflagellar transport (IFT) protein 25 in mammalian signaling transduction and flagellogenesis
por: Man, Yong-Hong, et al.
Publicado: (2021)

Phenomic technologies in drug discovery of neglected diseases
por: Nehrbass, Ulf
Publicado: (2011)

Databases and tools for constructing signal transduction networks in cancer
por: Nam, Seungyoon
Publicado: (2017)

Genetics of auditory mechano-electrical transduction
por: Michalski, Nicolas, et al.
Publicado: (2014)

Depolarizing Effectors of Bradykinin Signaling in Nociceptor Excitation in Pain Perception
por: Choi, Seung-In, et al.
Publicado: (2018)

Regulatory network of genes associated with stimuli sensing, signal transduction and physiological transformation of appressorium in Magnaporthe oryzae
por: Anjago, Wilfred Mabeche, et al.
Publicado: (2018)

The exciting potential of nanotherapy in brain-tumor targeted drug delivery approaches
por: Agrahari, Vivek
Publicado: (2017)

Small molecule activators of the p53 response
por: Ladds, Marcus J G W, et al.
Publicado: (2019)

PROM1-mediated cell signal transduction in cancer stem cells and hepatocytes
por: Bahn, Myeong-Suk, et al.
Publicado: (2023)

Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery
por: Park, Soo-Jin, et al.
Publicado: (2017)

Drug discovery: Insights from the invertebrate Caenorhabditis elegans
por: Giunti, Sebastián, et al.
Publicado: (2021)

Advancing drug discovery using the power of the human genome
por: Heilbron, Karl, et al.
Publicado: (2021)

Dyslipidemia modulates Müller glial sensing and transduction of ambient information
por: Lakk, Monika, et al.
Publicado: (2018)

Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction
por: Manigrasso, Michaele B., et al.
Publicado: (2016)

IP-FCM Measures Physiologic Protein-Protein Interactions Modulated by Signal Transduction and Small-Molecule Drug Inhibition
por: Smith, Stephen E. P., et al.
Publicado: (2012)

Coeliac disease: the showcase of interaction between genes, environment and immunology in chronic tissue inflammation
por: Sollid, Ludvig M
Publicado: (2011)

NOD2 function in Crohn's disease
por: Simmons, Alison
Publicado: (2011)

Regulation of early B cell tolerance checkpoints in humans
por: Meffre, Eric
Publicado: (2011)

IL-10 secreting regulatory B cells are potent arbiters of autoimmunity in both mouse and man
por: Mauri, Claudia, et al.
Publicado: (2011)

Autoimmunity and microbiota
por: Chervonsky, Alexander
Publicado: (2011)

Breakdown of antimicrobial host defense barrier as trigger of chronic inflammatory bowel diseases
por: Wehkamp, Jan
Publicado: (2011)

Anti-inflammatory and immune modulatory properties of mesenchymal stromal cells
por: Fibbe, Willem E
Publicado: (2011)

Regulatory T cells for the control of physiological and pathological immune responses
por: Sakaguchi, Shimon
Publicado: (2011)

Central nervous system effects of tumor necrosis factor alpha blockade
por: Schett, Georg
Publicado: (2011)

Epigenetic alterations in autoimmune disease
por: Ballestar, Esteban, et al.
Publicado: (2011)

Development of Foxp3+ regulatory T cell: epigenetics and more…
por: Hühn, Jochen
Publicado: (2011)

Omenn Syndrome: inflammation and autoimmunity
por: Villa, Anna
Publicado: (2011)

IL-1 blockade in inherited fever syndromes - what have we learnt?
por: Lachmann, Helen J
Publicado: (2011)

Biological ageing is a key determinant in systemic sclerosis
por: Shiels, Paul G, et al.
Publicado: (2011)

Immune-mediated muscle wasting and cell survival - the tale of a curious gene
por: Ross, James A
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_079jurdathdt12jflfio7e2dc2