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Decreased nitrite reductase activity of deoxyhemoglobin correlates with platelet activation in hemoglobin E/ß-thalassemia subjects

Nitric oxide (NO) can be generated from nitrite by reductase activity of deoxygenated hemoglobin (deoxyHb) apparently to facilitate tissue perfusion under hypoxic condition. Although hemoglobin E (HbE) solutions have been shown to exhibit decreased rate of nitrite reduction to NO, this observation h...

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Detalles Bibliográficos
Autores principales:	Chamchoi, Attaphon, Srihirun, Sirada, Paiboonsukwong, Kittiphong, Sriwantana, Thanaporn, Sathavorasmith, Piyadon, Pattanapanyasat, Kovit, Hirsch, Rhoda Elison, Schechter, Alan N., Sibmooh, Nathawut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147434/ https://www.ncbi.nlm.nih.gov/pubmed/30235277 http://dx.doi.org/10.1371/journal.pone.0203955

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