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Early CD8(+)-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT

In this single-center study we retrospectively evaluated the impact of early reconstitution of different lymphocyte subsets on patient outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We found that CD8(+) T-cell counts exceeding 50x10(6)/l as early as on day 28 post-tra...

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Detalles Bibliográficos
Autores principales: Ranti, Juha, Kurki, Samu, Salmenniemi, Urpu, Putkonen, Mervi, Salomäki, Soile, Itälä-Remes, Maija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147489/
https://www.ncbi.nlm.nih.gov/pubmed/30235281
http://dx.doi.org/10.1371/journal.pone.0204136