Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)

Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)et...

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Autores principales: Barbakadze, Vakhtang, Kemertelidze, Etheri, Targamadze, Iraida, Mulkijanyan, Karen, Shashkov, Alexander S., I.Usov, Anatolii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147524/
https://www.ncbi.nlm.nih.gov/pubmed/18007379
http://dx.doi.org/10.3390/10091135
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author Barbakadze, Vakhtang
Kemertelidze, Etheri
Targamadze, Iraida
Mulkijanyan, Karen
Shashkov, Alexander S.
I.Usov, Anatolii
author_facet Barbakadze, Vakhtang
Kemertelidze, Etheri
Targamadze, Iraida
Mulkijanyan, Karen
Shashkov, Alexander S.
I.Usov, Anatolii
author_sort Barbakadze, Vakhtang
collection PubMed
description Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene], according to IR and NMR spectroscopy. The Symphytum high-molecular preparations can modulate in vitro B- chronic lymphocytic leukaemia (B-CLL) cells apoptosis and cell cycle progression.
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spelling pubmed-61475242018-11-19 Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae) Barbakadze, Vakhtang Kemertelidze, Etheri Targamadze, Iraida Mulkijanyan, Karen Shashkov, Alexander S. I.Usov, Anatolii Molecules Article Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene], according to IR and NMR spectroscopy. The Symphytum high-molecular preparations can modulate in vitro B- chronic lymphocytic leukaemia (B-CLL) cells apoptosis and cell cycle progression. MDPI 2005-09-30 /pmc/articles/PMC6147524/ /pubmed/18007379 http://dx.doi.org/10.3390/10091135 Text en © 2005 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Barbakadze, Vakhtang
Kemertelidze, Etheri
Targamadze, Iraida
Mulkijanyan, Karen
Shashkov, Alexander S.
I.Usov, Anatolii
Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title_full Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title_fullStr Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title_full_unstemmed Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title_short Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S. Caucasicum Bieb. (Boraginaceae)
title_sort poly[3-(3,4-dihydroxyphenyl)glyceric acid], a new biologically active polymer from symphytum asperum lepech. and s. caucasicum bieb. (boraginaceae)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147524/
https://www.ncbi.nlm.nih.gov/pubmed/18007379
http://dx.doi.org/10.3390/10091135
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