Cargando…

Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region

Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mojzych, Mariusz, Rykowski, Andrzej, Wierzchowski, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147567/ https://www.ncbi.nlm.nih.gov/pubmed/18007523 http://dx.doi.org/10.3390/10101298

Ejemplares similares

Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3-e][1,2,4]triazine Derivatives
por: Bernat, Zofia, et al.
Publicado: (2020)

Synthesis, Structural Characterization, and Biological Activity of New Pyrazolo[4,3-e][1,2,4]triazine Acyclonucleosides
por: Mojzych, Mariusz, et al.
Publicado: (2020)

Synthesis of chiral pyrazolo[4,3-e][1,2,4]triazine sulfonamides with tyrosinase and urease inhibitory activity
por: Mojzych, Mariusz, et al.
Publicado: (2016)

1,3-Dimethyl-5-methylsulfonyl-1H-pyrazolo[4,3-e][1,2,4]triazine
por: Mojzych, Mariusz, et al.
Publicado: (2010)

Preparation of Novel Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides and Their Experimental and Computational Biological Studies
por: Kciuk, Mateusz, et al.
Publicado: (2022)

Genotoxicity of Novel Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides in Normal and Cancer Cells In Vitro
por: Kciuk, Mateusz, et al.
Publicado: (2023)

Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as Novel Potential Anticancer Agents: Cytotoxic and Genotoxic Activities In Vitro
por: Bukowski, Karol, et al.
Publicado: (2022)

Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as Novel Potential Anticancer Agents: Apoptosis, Oxidative Stress, and Cell Cycle Analysis
por: Bukowski, Karol, et al.
Publicado: (2023)

Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as an Important Scaffold for Anticancer Drug Discovery—In Vitro and In Silico Evaluation
por: Kciuk, Mateusz, et al.
Publicado: (2023)

The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2020)

2-(5,6-Diphenyl-1,2,4-triazin-3-yl)aniline
por: Mojzych, Mariusz, et al.
Publicado: (2012)

5,5′,6,6′-Tetramethyl-3,3′-bi-1,2,4-triazine
por: Wolińska, Ewa, et al.
Publicado: (2011)

The Anticancer Action of a Novel 1,2,4-Triazine Sulfonamide Derivative in Colon Cancer Cells
por: Gornowicz, Agnieszka, et al.
Publicado: (2021)

Efficient Routes to Pyrazolo[3,4-e][1,2,4]triazines and a New Ring System: [1,2,4]Triazino[5,6-d][1,2,3]triazines
por: Al-Matar, Hamad Mohamed, et al.
Publicado: (2010)

Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer
por: Hermanowicz, Justyna Magdalena, et al.
Publicado: (2021)

1,2-Bis[1-(3-methylsulfanyl-1,2,4-triazin-5-yl)ethylidene]diazane
por: Mojzych, Mariusz, et al.
Publicado: (2009)

CRYSTAL STRUCTURE OF 3-tert-BUTYL- PYRAZOLO[5,1-с][1,2,4]TRIAZINE-3,4-DIYL DICARBOXYLATES
por: Mironovich, L. M., et al.
Publicado: (2021)

2-(3-Chloro-5,6-diphenyl-2,5-dihydro-1,2,4-triazin-5-yl)-2-methylpropanenitrile
por: Wolińska, Ewa, et al.
Publicado: (2012)

Xanthone-1,2,4-triazine and Acridone-1,2,4-triazine Conjugates: Synthesis and Anticancer Activity
por: Santra, Sougata, et al.
Publicado: (2023)

Synthesis, biological activity and molecular modeling study of novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines
por: El-Reedy, Ahmed A. M., et al.
Publicado: (2020)

Synthesis and Electrophilic Substitutions of Novel Pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines
por: Atta, Kamal F.M.
Publicado: (2011)

Synthesis and Antimicrobial Activity of Some New Pyrazole, Fused Pyrazolo[3,4-d]-pyrimidine and Pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine Derivatives
por: Abunada, Nada M., et al.
Publicado: (2008)

Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent
por: El-Kalyoubi, Samar A.
Publicado: (2018)

Discovery of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations
por: Nassar, Ibrahim F., et al.
Publicado: (2022)

Synthesis and Antibacterial Activities of Novel 2,5-Diphenylindolo[2,3-e] Pyrazolo[1',5':3",4"]pyrimido[2",1"-c][1,2,4]triazines
por: Atta, Kamal F.M., et al.
Publicado: (2011)

Strain-Promoted Reaction of 1,2,4-Triazines with Bicyclononynes
por: Horner, Katherine A, et al.
Publicado: (2015)

Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity
por: Mandour, Asmaa A., et al.
Publicado: (2022)

Synthesis of Energetic 7-Nitro-3,5-dihydro-4H-pyrazolo[4,3-d][1,2,3]triazin-4-one Based on a Novel Hofmann-Type Rearrangement
por: Bi, Fu-Qiang, et al.
Publicado: (2021)

5,6-Dimethyl-1,2,4-triazin-3-amine
por: Wu, Man-Hua, et al.
Publicado: (2011)

3-Methylsulfanyl-5-phenyl-1,2,4-triazine
por: Hamri, Salha, et al.
Publicado: (2014)

Synthesis and Antimicrobial Activity of Some New Pyrazoles, Fused Pyrazolo[3,4-d]-pyrimidine and 1,2-Dihydroimidazo-[2,1-c][1,2,4]triazin-6-one Derivatives
por: Gomha, Sobhi Mohamed, et al.
Publicado: (2011)

1H-Pyrazolo[4,3-g]benzothiazol-7-amine
por: Camacho, José R., et al.
Publicado: (2009)

Straightforward and Efficient Protocol for the Synthesis of Pyrazolo [4,3-b]pyridines and Indazoles
por: Nikol’skiy, Vladislav V., et al.
Publicado: (2023)

Polymerization Effects on the Decomposition of a Pyrazolo‐Triazine at high Temperatures and Pressures
por: Li, Yaojiang, et al.
Publicado: (2020)

The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions
por: Siegl, Sebastian J., et al.
Publicado: (2017)

Revisiting the Synthesis of Functionally Substituted 1,4-Dihydrobenzo[e][1,2,4]triazines
por: Epishina, Margarita A., et al.
Publicado: (2022)

Synthesis of new pyrazolo[1,2,3]triazines by cyclative cleavage of pyrazolyltriazenes
por: Wippert, Nicolai, et al.
Publicado: (2021)

5,6-Diphenyl-3-(3-pyridyl)-1,2,4-triazine
por: Jian, Fang-Fang, et al.
Publicado: (2010)

First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions Thereof
por: Bokor, Éva, et al.
Publicado: (2022)

Regio- and Diastereoselective 1,3-Dipolar Cycloadditions of 1,2,4-Triazin-1-ium Ylides: a Straightforward Synthetic Route to Polysubstituted Pyrrolo[2,1-f][1,2,4]triazines
por: Galeta, Juraj, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tn3gppg1uhkre8bhntru99ummh