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Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia

In mammalians, advancing age is associated with sarcopenia, the progressive and involuntary loss of muscle mass and strength. Hyperphosphatemia is an aging-related condition involved in several pathologies. The aim of this work was to assess whether hyperphosphatemia plays a role in the age-related...

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Detalles Bibliográficos
Autores principales: Sosa, Patricia, Alcalde-Estevez, Elena, Plaza, Patricia, Troyano, Nuria, Alonso, Cristina, Martínez-Arias, Laura, Evelem de Melo Aroeira, Andresa, Rodriguez-Puyol, Diego, Olmos, Gemma, López-Ongil, Susana, Ruíz-Torres, María P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147593/
https://www.ncbi.nlm.nih.gov/pubmed/30271655
http://dx.doi.org/10.14336/AD.2017.1214