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An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147620/ https://www.ncbi.nlm.nih.gov/pubmed/18007540 http://dx.doi.org/10.3390/10121438 |
| Sumario: | A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries. |
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