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An Efficient Protocol for the Solid-phase Synthesis of Malondiamides

A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.

Detalles Bibliográficos
Autores principales: Vögtle, Markus M., Marzinzik, Andreas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147620/
https://www.ncbi.nlm.nih.gov/pubmed/18007540
http://dx.doi.org/10.3390/10121438
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author Vögtle, Markus M.
Marzinzik, Andreas L.
author_facet Vögtle, Markus M.
Marzinzik, Andreas L.
author_sort Vögtle, Markus M.
collection PubMed
description A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.
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spelling pubmed-61476202018-11-16 An Efficient Protocol for the Solid-phase Synthesis of Malondiamides Vögtle, Markus M. Marzinzik, Andreas L. Molecules Article A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries. MDPI 2005-12-31 /pmc/articles/PMC6147620/ /pubmed/18007540 http://dx.doi.org/10.3390/10121438 Text en © 2005 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Vögtle, Markus M.
Marzinzik, Andreas L.
An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title_full An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title_fullStr An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title_full_unstemmed An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title_short An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
title_sort efficient protocol for the solid-phase synthesis of malondiamides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147620/
https://www.ncbi.nlm.nih.gov/pubmed/18007540
http://dx.doi.org/10.3390/10121438
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