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An Efficient Protocol for the Solid-phase Synthesis of Malondiamides
A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147620/ https://www.ncbi.nlm.nih.gov/pubmed/18007540 http://dx.doi.org/10.3390/10121438 |
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author | Vögtle, Markus M. Marzinzik, Andreas L. |
author_facet | Vögtle, Markus M. Marzinzik, Andreas L. |
author_sort | Vögtle, Markus M. |
collection | PubMed |
description | A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries. |
format | Online Article Text |
id | pubmed-6147620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61476202018-11-16 An Efficient Protocol for the Solid-phase Synthesis of Malondiamides Vögtle, Markus M. Marzinzik, Andreas L. Molecules Article A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries. MDPI 2005-12-31 /pmc/articles/PMC6147620/ /pubmed/18007540 http://dx.doi.org/10.3390/10121438 Text en © 2005 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes. |
spellingShingle | Article Vögtle, Markus M. Marzinzik, Andreas L. An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title | An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title_full | An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title_fullStr | An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title_full_unstemmed | An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title_short | An Efficient Protocol for the Solid-phase Synthesis of Malondiamides |
title_sort | efficient protocol for the solid-phase synthesis of malondiamides |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147620/ https://www.ncbi.nlm.nih.gov/pubmed/18007540 http://dx.doi.org/10.3390/10121438 |
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