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Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation

Transcription factor nuclear factor kappa B (NF-κB) regulates cellular responses to environmental cues. Many stimuli induce NF-κB transiently, making time-dependent transcriptional outputs a fundamental feature of NF-κB activation. Here we show that NF-κB target genes have distinct kinetic patterns...

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Detalles Bibliográficos
Autores principales: Zhao, Mingming, Joy, Jaimy, Zhou, Weiqiang, De, Supriyo, Wood, William H., Becker, Kevin G., Ji, Hongkai, Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147668/
https://www.ncbi.nlm.nih.gov/pubmed/30199532
http://dx.doi.org/10.1371/journal.pbio.2006347