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Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation
Transcription factor nuclear factor kappa B (NF-κB) regulates cellular responses to environmental cues. Many stimuli induce NF-κB transiently, making time-dependent transcriptional outputs a fundamental feature of NF-κB activation. Here we show that NF-κB target genes have distinct kinetic patterns...
Autores principales: | Zhao, Mingming, Joy, Jaimy, Zhou, Weiqiang, De, Supriyo, Wood, William H., Becker, Kevin G., Ji, Hongkai, Sen, Ranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147668/ https://www.ncbi.nlm.nih.gov/pubmed/30199532 http://dx.doi.org/10.1371/journal.pbio.2006347 |
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