Covalent Polymer-Drug Conjugates

In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and li...

Descripción completa

Detalles Bibliográficos
Autores principales: Elvira, Carlos, Gallardo, Alberto, Roman, Julio San, Cifuentes, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147706/
https://www.ncbi.nlm.nih.gov/pubmed/18007281
http://dx.doi.org/10.3390/10010114
Descripción
Sumario:In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and polymer-proteins conjugates recently developed.

Ejemplares similares