Covalent Polymer-Drug Conjugates

In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and li...

Descripción completa

Detalles Bibliográficos
Autores principales: Elvira, Carlos, Gallardo, Alberto, Roman, Julio San, Cifuentes, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147706/
https://www.ncbi.nlm.nih.gov/pubmed/18007281
http://dx.doi.org/10.3390/10010114
_version_ 1783356609074823168
author Elvira, Carlos
Gallardo, Alberto
Roman, Julio San
Cifuentes, Alejandro
author_facet Elvira, Carlos
Gallardo, Alberto
Roman, Julio San
Cifuentes, Alejandro
author_sort Elvira, Carlos
collection PubMed
description In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and polymer-proteins conjugates recently developed.
format Online
Article
Text
id pubmed-6147706
institution National Center for Biotechnology Information
language English
publishDate 2005
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61477062018-11-19 Covalent Polymer-Drug Conjugates Elvira, Carlos Gallardo, Alberto Roman, Julio San Cifuentes, Alejandro Molecules Review In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and polymer-proteins conjugates recently developed. MDPI 2005-01-31 /pmc/articles/PMC6147706/ /pubmed/18007281 http://dx.doi.org/10.3390/10010114 Text en © 2005 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Review
Elvira, Carlos
Gallardo, Alberto
Roman, Julio San
Cifuentes, Alejandro
Covalent Polymer-Drug Conjugates
title Covalent Polymer-Drug Conjugates
title_full Covalent Polymer-Drug Conjugates
title_fullStr Covalent Polymer-Drug Conjugates
title_full_unstemmed Covalent Polymer-Drug Conjugates
title_short Covalent Polymer-Drug Conjugates
title_sort covalent polymer-drug conjugates
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147706/
https://www.ncbi.nlm.nih.gov/pubmed/18007281
http://dx.doi.org/10.3390/10010114
work_keys_str_mv AT elviracarlos covalentpolymerdrugconjugates
AT gallardoalberto covalentpolymerdrugconjugates
AT romanjuliosan covalentpolymerdrugconjugates
AT cifuentesalejandro covalentpolymerdrugconjugates

Ejemplares similares