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Epac1 protects the retina against ischemia/reperfusion-induced neuronal and vascular damage
We had previously reported that exchange protein for cAMP 1 (Epac1) reduced inflammatory mediators in the retina of mice and in retinal endothelial cells (REC). Since ischemia can induce retinal damage potentially through activation of inflammatory cascades, we hypothesized that Epac1 would protect...
Autores principales: | Liu, Li, Jiang, Youde, Steinle, Jena J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147720/ https://www.ncbi.nlm.nih.gov/pubmed/30235337 http://dx.doi.org/10.1371/journal.pone.0204346 |
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