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Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death

Oxidative stress can cause apoptosis in neurons and may result in neurodegenerative diseases. However, the signaling mechanisms leading to oxidative stress–induced neuronal apoptosis are not fully understood. Oxidative stress stimulates aberrant activation of cyclin-dependent kinase 5 (CDK5), though...

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Detalles Bibliográficos
Autores principales:	Guo, Dong, Xie, Wenting, Xiong, Pan, Li, Huifang, Wang, Siqi, Chen, Guimiao, Gao, Yuehong, Zhou, Jiechao, Zhang, Ye, Bu, Guojun, Xue, Maoqiang, Zhang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147799/ https://www.ncbi.nlm.nih.gov/pubmed/30237421 http://dx.doi.org/10.1038/s41419-018-0983-1

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