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Spinal tuberculosis: CT and MRI features

BACKGROUND: Spinal tuberculosis (TB) is perhaps the most clinically important extrapulmonary form of the disease. Early recognition is therefore necessary to minimize residual spinal deformity and/or permanent neurological deficit. We defined the CT and MRI image morphology of spinal TB and correlat...

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Autores principales: Sinan, Tariq, Al-Khawari, Hana, Ismail, Mohammed, Ben-Nakhi, Abdulmohsen, Sheikh, Mehraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147852/
https://www.ncbi.nlm.nih.gov/pubmed/15646161
http://dx.doi.org/10.5144/0256-4947.2004.437
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author Sinan, Tariq
Al-Khawari, Hana
Ismail, Mohammed
Ben-Nakhi, Abdulmohsen
Sheikh, Mehraj
author_facet Sinan, Tariq
Al-Khawari, Hana
Ismail, Mohammed
Ben-Nakhi, Abdulmohsen
Sheikh, Mehraj
author_sort Sinan, Tariq
collection PubMed
description BACKGROUND: Spinal tuberculosis (TB) is perhaps the most clinically important extrapulmonary form of the disease. Early recognition is therefore necessary to minimize residual spinal deformity and/or permanent neurological deficit. We defined the CT and MRI image morphology of spinal TB and correlated the imaging features of these two modalities. METHODS: CT (29 patients) and MRI (11 patients) images were retrospectively analyzed in 30 patients with proved spinal TB. CT and MRI findings were compared in cases with both imaging tests (10 cases). The parameters assessed were the type and extent of bone and soft tissue involvement. RESULTS: The majority of the 30 patients were males (n=18) in the 30–49 year age group (43%). The most common clinical presentation was backache (73.3%) followed by fever (63.3%) and malaise (36.6%). The lumbar spine was the commonest site of the disease (43.3%) followed by the thoracic region (36.6%). A fragmentary type of bone destruction was the most frequent CT feature of the disease (48.2%) followed by the lytic type (24.1%). Intervertebral disc destruction (72%) and paravertebral mass/abscess (65.5%) were other features. Of the 11 patients who had an MRI, contiguous vertebral disease with disc destruction was seen in 10 cases. In 4 patients, there was distant vertebral disease in addition to the disease at the symptomatic site. CONCLUSIONS: MRI offers excellent visualization of the bone and soft tissue components of spinal tuberculosis and helps to identify disease at distant asymptomatic sites. CT is useful in assessing bone destruction, but is less accurate in defining the epidural extension of the disease and therefore its effect on neural structures. MR imaging clearly demonstrated the extent of soft tissue disease and its effect on the theca/cord and foramen in cases with doubtful CT findings.
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spelling pubmed-61478522018-09-21 Spinal tuberculosis: CT and MRI features Sinan, Tariq Al-Khawari, Hana Ismail, Mohammed Ben-Nakhi, Abdulmohsen Sheikh, Mehraj Ann Saudi Med Original Article BACKGROUND: Spinal tuberculosis (TB) is perhaps the most clinically important extrapulmonary form of the disease. Early recognition is therefore necessary to minimize residual spinal deformity and/or permanent neurological deficit. We defined the CT and MRI image morphology of spinal TB and correlated the imaging features of these two modalities. METHODS: CT (29 patients) and MRI (11 patients) images were retrospectively analyzed in 30 patients with proved spinal TB. CT and MRI findings were compared in cases with both imaging tests (10 cases). The parameters assessed were the type and extent of bone and soft tissue involvement. RESULTS: The majority of the 30 patients were males (n=18) in the 30–49 year age group (43%). The most common clinical presentation was backache (73.3%) followed by fever (63.3%) and malaise (36.6%). The lumbar spine was the commonest site of the disease (43.3%) followed by the thoracic region (36.6%). A fragmentary type of bone destruction was the most frequent CT feature of the disease (48.2%) followed by the lytic type (24.1%). Intervertebral disc destruction (72%) and paravertebral mass/abscess (65.5%) were other features. Of the 11 patients who had an MRI, contiguous vertebral disease with disc destruction was seen in 10 cases. In 4 patients, there was distant vertebral disease in addition to the disease at the symptomatic site. CONCLUSIONS: MRI offers excellent visualization of the bone and soft tissue components of spinal tuberculosis and helps to identify disease at distant asymptomatic sites. CT is useful in assessing bone destruction, but is less accurate in defining the epidural extension of the disease and therefore its effect on neural structures. MR imaging clearly demonstrated the extent of soft tissue disease and its effect on the theca/cord and foramen in cases with doubtful CT findings. King Faisal Specialist Hospital and Research Centre 2004 /pmc/articles/PMC6147852/ /pubmed/15646161 http://dx.doi.org/10.5144/0256-4947.2004.437 Text en Copyright © 2004, Annals of Saudi Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Sinan, Tariq
Al-Khawari, Hana
Ismail, Mohammed
Ben-Nakhi, Abdulmohsen
Sheikh, Mehraj
Spinal tuberculosis: CT and MRI features
title Spinal tuberculosis: CT and MRI features
title_full Spinal tuberculosis: CT and MRI features
title_fullStr Spinal tuberculosis: CT and MRI features
title_full_unstemmed Spinal tuberculosis: CT and MRI features
title_short Spinal tuberculosis: CT and MRI features
title_sort spinal tuberculosis: ct and mri features
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147852/
https://www.ncbi.nlm.nih.gov/pubmed/15646161
http://dx.doi.org/10.5144/0256-4947.2004.437
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