Cargando…

Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells

Diabetes mellitus affects a large number of men of reproductive age and it usually leads to serious reproductive disorders. However, the underlying mechanisms and specific therapies still remain largely unknown. We observed Leydig cell loss in the testes of diabetic mice. Continuous high glycemic st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Zhaoyu, Xu, Shuanshuan, Hu, Shuxian, Yang, Hong, Zhou, Zhe, Sidhu, Kuldip, Miao, Yiliang, Liu, Zhonghua, Shen, Wei, Reiter, Russel J., Hua, Jinlian, Peng, Sha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148071/ https://www.ncbi.nlm.nih.gov/pubmed/30237484 http://dx.doi.org/10.1038/s41419-018-0956-4

Ejemplares similares

Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
por: Nóbrega, Rafael Henrique, et al.
Publicado: (2010)

Spermatogonial Stem Cell Markers and Niche in Equids
por: Costa, Guilherme M. J., et al.
Publicado: (2012)

Perturbation of microRNA signalling by doxorubicin in spermatogonial, Leydig and Sertoli cell lines in vitro
por: Akinjo, Oluwajoba O., et al.
Publicado: (2018)

Sertoli cell ablation and replacement of the spermatogonial niche in mouse
por: Yokonishi, Tetsuhiro, et al.
Publicado: (2020)

Dissecting the spermatogonial stem cell niche using spatial transcriptomics
por: Rajachandran, Shreya, et al.
Publicado: (2023)

Melatonin improves spermatogonial stem cells transplantation efficiency in azoospermic mice
por: Gholami, Mohammadreza, et al.
Publicado: (2014)

WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche
por: Jia, Gong-Xue, et al.
Publicado: (2020)

Sertoli, Leydig, and Spermatogonial Cells’ Specific Gene and Protein Expressions as Dog Testes Evolve from Immature into Mature States
por: Kasimanickam, Vanmathy R., et al.
Publicado: (2022)

Melatonin and Carbohydrate Metabolism in Plant Cells
por: Arnao, Marino B., et al.
Publicado: (2021)

Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system
por: Deng, Shou-Long, et al.
Publicado: (2017)

Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration
por: Luchetti, Francesca, et al.
Publicado: (2022)

Decoding the spermatogonial stem cell niche under physiological and recovery conditions in adult mice and humans
por: Jin, Cheng, et al.
Publicado: (2023)

Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders
por: Loh, Doris, et al.
Publicado: (2021)

The Multiple Functions of Melatonin: Applications in the Military Setting
por: Gancitano, Giuseppe, et al.
Publicado: (2022)

Eif2s3y Promotes the Proliferation of Spermatogonial Stem Cells by Activating ERK Signaling
por: Zhang, Mengfei, et al.
Publicado: (2021)

A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
por: Sagaradze, Georgy, et al.
Publicado: (2019)

Human spermatogonial stem cells and their niche in male (in)fertility: novel concepts from single-cell RNA-sequencing
por: Di Persio, Sara, et al.
Publicado: (2022)

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells
por: Gao, Yuan, et al.
Publicado: (2019)

Melatonin Protects Cultured Tobacco Cells against Lead-Induced Cell Death via Inhibition of Cytochrome c Translocation
por: Kobylińska, Agnieszka, et al.
Publicado: (2017)

Light, Water, and Melatonin: The Synergistic Regulation of Phase Separation in Dementia
por: Loh, Doris, et al.
Publicado: (2023)

Clinical Uses of Melatonin in Pediatrics
por: Sánchez-Barceló, Emilio J., et al.
Publicado: (2011)

Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis
por: Rebourcet, Diane, et al.
Publicado: (2014)

E-cadherin maintains the undifferentiated state of mouse spermatogonial progenitor cells via β-catenin
por: Song, Weixiang, et al.
Publicado: (2022)

AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment
por: Xu, J, et al.
Publicado: (2015)

Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse
por: Wu, Chongyang, et al.
Publicado: (2016)

Melatonin reduces lipid peroxidation and membrane viscosity
por: Reiter, Russel J., et al.
Publicado: (2014)

Melatonin: Regulation of Prion Protein Phase Separation in Cancer Multidrug Resistance
por: Loh, Doris, et al.
Publicado: (2022)

Melatonin and non-small cell lung cancer: new insights into signaling pathways
por: Pourhanifeh, Mohammad Hossein, et al.
Publicado: (2019)

Melatonin in cryopreservation media improves transplantation efficiency of frozen–thawed spermatogonial stem cells into testes of azoospermic mice
por: Kazemzadeh, Shokoofeh, et al.
Publicado: (2022)

Effect of Removal of Spermatogonial Stem Cells (SSCs) from In Vitro Culture on Gene Expression of Niche Factors in Bovine
por: Akbarinejad, Vahid, et al.
Publicado: (2016)

Editorial: Therapeutic Advances in Melatonin Research
por: López-Muñoz, Francisco, et al.
Publicado: (2022)

MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins
por: Chen, Jian, et al.
Publicado: (2017)

Plasticity of spermatogonial stem cells
por: Cooke, Paul S, et al.
Publicado: (2015)

Is melatonin deficiency a unifying pathomechanism of high risk patients with COVID-19?
por: Simko, Fedor, et al.
Publicado: (2020)

Neurotoxins: Free Radical Mechanisms and Melatonin Protection
por: Reiter, Russel J., et al.
Publicado: (2010)

Influence of fetal Leydig cells on the development of adult Leydig cell population in rats
por: SU, Dong-Mei, et al.
Publicado: (2018)

Insights into the Development of the Adult Leydig Cell Lineage from Stem Leydig Cells
por: Ye, Leping, et al.
Publicado: (2017)

Melatonin as a rational alternative in the conservative treatment of resistant hypertension
por: Simko, Fedor, et al.
Publicado: (2019)

Tunneling nanotubes and mesenchymal stem cells: New insights into the role of melatonin in neuronal recovery
por: Luchetti, Francesca, et al.
Publicado: (2022)

Mechanisms of Melatonin in Alleviating Alzheimer’s Disease
por: Shukla, Mayuri, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_t2el4adaq1ff23dl5oll9rpgfj