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O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma

Rab3A is a small Ras-like GTPase critical for membrane traffic. Although the functions of Rab3A have been reported in several cancers, the roles of Rab3A in hepatocellular carcinoma (HCC) have never been determined. To investigate the potential roles of Rab3A in HCC progression, we first determined...

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Detalles Bibliográficos
Autores principales: Wu, Weicheng, Zheng, Xixi, Wang, Jing, Yang, Tianxiao, Dai, Wenjuan, Song, Shushu, Fang, Lan, Wang, Yilin, Gu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148238/
https://www.ncbi.nlm.nih.gov/pubmed/30237463
http://dx.doi.org/10.1038/s41419-018-0961-7