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Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway

Arsenic exposure causes nonalcoholic steatohepatitis (NASH). Inflammation is a key contributor to the pathology of nonalcoholic fatty liver disease (NAFLD), including NASH. However, it is unclear how arsenic induces inflammation. In mouse livers, we show that arsenic trioxide (As(2)O(3)) induced NAS...

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Detalles Bibliográficos
Autores principales: Qiu, Tianming, Pei, Pei, Yao, Xiaofeng, Jiang, Liping, Wei, Sen, Wang, Zhidong, Bai, Jie, Yang, Guang, Gao, Ni, Yang, Lei, Qi, Shuangyue, Yan, Rushan, Liu, Xiaofang, Sun, Xiance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148242/
https://www.ncbi.nlm.nih.gov/pubmed/30237538
http://dx.doi.org/10.1038/s41419-018-1004-0