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Design and Synthesis of New 1,3,5‐Trisubstituted Triazines for the Treatment of Cancer and Inflammation
Low‐molecular‐weight synthetic molecules 1 with the general 2‐(fluorophenylamino)‐4,6‐disubstituted 1,3,5‐triazine structure and showing anti‐inflammatory and anticancer activities were explored. Structure–activity relationship studies demonstrated the importance of the aminopentyl chain, the 3‐ or...
Autores principales: | Zacharie, Boulos, Abbott, Shaun D., Duceppe, Jean‐Simon, Gagnon, Lyne, Grouix, Brigitte, Geerts, Lilianne, Gervais, Liette, Sarra‐Bournet, François, Perron, Valérie, Wilb, Nicole, Penney, Christopher L., Laurin, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148406/ https://www.ncbi.nlm.nih.gov/pubmed/30258746 http://dx.doi.org/10.1002/open.201800136 |
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